Addyi helps balance neurotransmitters like dopamine, serotonin, and norepinephrine to support sexual desire.
The Clinically Proven Treatment for Low Sexual Desire
Real Science.
Real Results.
The exact way Addyi works is unknown.
IN CLINICAL TRIALS1, WOMEN ON ADDYI EXPERIENCED:
More Interest in Sex
More Satisfying Sex
Less Stress (From Low Libido)
1. ADDYI was studied in four 6-month clinical trials in more than 3,200 women with low sexual desire, of whom 902 were postmenopausal and under 65. Participants were randomly assigned to receive ADDYI or a placebo. Researchers evaluated changes in the number of sexually satisfying events, desire, and stress due to frustrating low sexual desire.
The Clinically Proven Treatment for Low Sexual Desire
Real Science.
Real Results.
Addyi helps balance neurotransmitters like dopamine, serotonin, and norepinephrine to support sexual desire.
The exact way Addyi works is unknown.
IN CLINICAL TRIALS1, WOMEN ON ADDYI EXPERIENCED:
More Interest in Sex
More Satisfying Sex
Less Stress (From Low Libido)
1. ADDYI was studied in four 6-month clinical trials in more than 3,200 women with low sexual desire, of whom 902 were postmenopausal and under 65. Participants were randomly assigned to receive ADDYI or a placebo. Researchers evaluated changes in the number of sexually satisfying events, desire, and stress due to frustrating low sexual desire.
Are you a healthcare provider?
The #1 Prescribed Treatment for frustrating Low Libido1
Getting Addyi doesn’t have to be complicated or expensive. Patients with insurance coverage pay as little as $20 per month2. Paying cash? Addyi is only $149/month through PHILRx, delivered free to your door, and their coupon is automatically applied.
1. IQVIA Monthly Total Prescriptions Volume Data Comparing Addyi vs Vyleesi in the US. March 2026
2. Eligible patients only. Restrictions apply. See Terms and Conditions
The #1 Prescribed Treatment for frustrating Low Libido1
Getting Addyi doesn’t have to be complicated or expensive. Patients with insurance coverage pay as little as $20 per month2. Paying cash? Addyi is only $149/month through PHILRx, delivered free to your door, and their coupon is automatically applied.
1. IQVIA Monthly Total Prescriptions Volume Data Comparing Addyi vs Vyleesi in the US. March 2026
2. Eligible patients only. Restrictions apply. See Terms and Conditions
Desire Starts in the Brain...
And Sometimes It Hits Pause. When brain chemicals fall out of balance, sexual desire can drop too. That’s what happens with HSDD.
Desire Starts in the Brain...
And Sometimes It Hits Pause. When brain chemicals fall out of balance, sexual desire can drop too. That’s what happens with HSDD.
What women are saying
“Addyi helped me reconnect with my desire in a way that finally felt sustainable.”
Katie T, 51, actual Addyi patient
“After menopause, I thought losing desire was just something I had to accept. Addyi helped me realize I didn’t.”
Hillary F, 55, actual Addyi patient
“For the first time in a long time, I feel more engaged and satisfied during sex, not distracted or checked out.”
Cassie W, 48, actual Addyi patient
“I had no desire, I thought it was just me… something that happened as I got older. But then one of my girlfriends told me about Addyi. All I have to say is OMG… I wish I had learned about this sooner!”
Allie C, 50, acutal Addyi patient
“Addyi helped me reconnect with my desire in a way I’d been missing for years.”
Margaret B, 64, actual Addyi patient
“I used to dread going to bed with my husband because I was never in the mood… he thought it was his fault. We were really struggling. Then we found Addyi!”
Kendall G, 31, actual Addyi patient
What women are saying
“Addyi helped me reconnect with my desire in a way that finally felt sustainable.”
Katie T, 51, actual Addyi patient
“After menopause, I thought losing desire was just something I had to accept. Addyi helped me realize I didn’t.”
Hillary F, 55, actual Addyi patient
“For the first time in a long time, I feel more engaged and satisfied during sex, not distracted or checked out.”
Cassie W, 48, actual Addyi patient
“I had no desire, I thought it was just me… something that happened as I got older. But then one of my girlfriends told me about Addyi. All I have to say is OMG… I wish I had learned about this sooner!”
Allie C, 50, actual Addyi patient
“Addyi helped me reconnect with my desire in a way I’d been missing for years.”
Margaret B, 64, actual Addyi patient
“I used to dread going to bed with my husband because I was never in the mood… he thought it was his fault. We were really struggling. Then we found Addyi!”
Kendall G, 31, actual Addyi patient
The Big Pink Fight for the Little Pink Pill
Before Addyi, there were 26 FDA-approved treatments for male sexual dysfunction. And exactly zero for women. Not because the need wasn’t there. But because there was simply no desire to take women’s desire seriously.
So we did. Seriously.
The Big Pink Fight for the Little Pink Pill
Before Addyi, there were 26 FDA-approved treatments for male sexual dysfunction. And exactly zero for women. Not because the need wasn’t there. But because there was simply no desire to take women’s desire seriously.
So we did. Seriously.
EVERYONE’S TALKING ABOUT ADDYI
EVERYONE’S TALKING ABOUT ADDYI
Find out if treatment is right for you.
Your online visit today is only $49 $19.
By clicking here you will go to a third-party telemedicine provider.
See full prescribing Information including Boxed Warning regarding severe low blood pressure and fainting in certain settings at addyi.com/pi
Find out if treatment is right for you.
Your online visit today is only $49 $19.
By clicking here you will go to a third-party telemedicine provider.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about ADDYI?
ADDYI can cause severe low blood pressure and fainting (loss of consciousness). Your risk is higher if you drink alcohol close to your dose. Do not take ADDYI with certain medicines or if you have liver problems. To lower your risk of low blood pressure and fainting:
- Do not drink alcohol close to the time you take ADDYI. Skip your dose if you had 3 or more drinks before bedtime. Wait at least 2 hours after 1–2 alcoholic drinks before taking ADDYI. After taking ADDYI, do not drink alcohol until the next day
- Talk to your doctor about the medicines and supplements you take and before starting any new ones
- Do not take ADDYI if you have liver problems
If you feel dizzy or lightheaded after taking ADDYI, lie down right away. Get medical help if symptoms do not go away.
Who should not take ADDYI?
Do not take ADDYI if you:
take certain medicines that increase ADDYI levels in your blood (including some treatments for HIV, fungal infections, antibiotics, hepatitis C, heart conditions, or depression such as nefazodone)
- have liver problems
- are allergic to ADDYI
What should I tell my doctor before taking ADDYI?
Tell your doctor about all your medical conditions, including if you:
- drink alcohol, use drugs, or have a history of substance abuse
- have ever had depression or other mental health conditions
- have low blood pressure or a condition that can cause it
- are pregnant, planning pregnancy, or breastfeeding
Tell your doctor or pharmacist about all medicines and supplements you take, as they may interact with ADDYI.
What should I avoid while taking ADDYI?
- Do not drink alcohol close to your dose
- Do not drive or operate machinery for at least 6 hours after taking ADDYI
- Do not drink grapefruit juice
- Do not take supplements such as St. John’s Wort, ginkgo, or resveratrol, or certain medicines like cimetidine, without talking to your doctor
What are the possible side effects of ADDYI?
ADDYI can cause serious side effects, including:
- See “What is the most important information I should know about ADDYI?”
- sleepiness
- low blood pressure and fainting
The most common side effects include:
- dizziness
- nausea
- tiredness
- trouble sleeping
- dry mouth
This is not a complete list of side effects. Call your doctor for medical advice.
What is ADDYI?
ADDYI is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in women < 65 years of age who have not had problems with low sexual desire in the past, no matter the type of sexual activity, situation, or sexual partner, and it is troubling to them. Their low sexual desire is not due to a medical or mental health problem, problems in the relationship, medicine or other drug use.
ADDYI is not for use in men or to improve sexual performance.