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My sexual appetite has vanished...

UNDERSTANDING HSDD

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My sexual appetite has vanished...

UNDERSTANDING HSDD

It’s not you. It’s not me. It’s HSDD.

Hypoactive (low) Sexual Desire Disorder (HSDD) affects 1 in 10 premenopausal women.1 It’s characterized by a lack of interest in sex that’s lasted more than 6 months, and is causing personal frustration.

You may not have known it has a name but you’ve already been talking about it. That “IT” is being frustrated by your low libido – or your libido that’s not what it once was. HSDD has been known as a medical condition for nearly half a century – so you may not have called it by name but you’ve definitely called it out.

You may not have known it has a name but you’ve already been talking about it. That “IT” is being frustrated by your low libido – or your libido that’s not what it once was. HSDD has been known as a medical condition for nearly half a century – so you may not have called it by name but you’ve definitely called it out.

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It's in my head...

The feeling of desire starts in your brain. Women with HSDD likely can’t turn off their “everyday brain” to prioritize their own pleasure. Sound familiar?

HSDD is believed to be caused by an imbalance of chemicals in the brain that affects a woman’s sexual response. Check out the two brain scans – these two women were both exposed to erotic material. The brain without HSDD activates as it should, while the brain with HSDD remains nearly dormant.2,3,4

It’s in my head…

The feeling of desire starts in your brain. Women with HSDD likely can’t turn off their “everyday brain” to prioritize their own pleasure. Sound familiar?

HSDD is believed to be caused by an imbalance of chemicals in the brain that affects a woman’s sexual response. Check out the two brain scans – these two women were both exposed to erotic material. The brain without HSDD activates as it should, while the brain with HSDD remains nearly dormant.2,3,4

How is HSDD diagnosed?

It’s EASY. There’s a 5 question screener which is used by healthcare providers to diagnose HSDD. It’s called the DSDS, or Decreased Sexual Desire Screener.5

Help start the dialogue about your sexual desire by answering the five questions below and taking a screenshot of your results to show your healthcare provider.

Meet Addyi. Meet the you that YOU remember.

Addyi is the first and only FDA-approved non-hormonal pill to treat HSDD. In studies, Addyi demonstrated noticeable improvement of HSDD symptoms, including: adding desire, adding the number of satisfying sexual events, and reducing distress.

Meet Addyi.

Meet the you that

YOU remember.

Addyi is the first and only FDA-approved non-hormonal pill to treat HSDD. In studies, Addyi demonstrated noticeable improvement of HSDD symptoms, including: adding desire, adding the number of satisfying sexual events, and reducing distress.

Indication and Important Safety Information, including Boxed Warning

INDICATION

Addyi® (flibanserin) tablets is a prescription medicine used to treat Hypoactive (low) Sexual Desire Disorder (HSDD) in women who have not gone through menopause, who have not had problems with low sexual desire in the past, and who have low sexual desire no matter the type of sexual activity, the situation, or the sexual partner. Women with HSDD have low sexual desire that is troubling to them. Their low sexual desire is not due to:

  • a medical or mental health problem
  • problems in the relationship
  • medicine or other drug use

Addyi is not for the treatment of HSDD in women who have gone through menopause or in men, or to improve sexual performance. Addyi is not for use in children.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ADDYI (add-ee)?

Your risk of severe low blood pressure and fainting (loss of consciousness) is increased if you take ADDYI and:

  • drink alcohol close in time to when you take your ADDYI dose.
    • Wait at least 2 hours after drinking 1 or 2 standard alcoholic drinks before taking ADDYI at bedtime.

Examples of 1 standard alcoholic drink include:

      • one 12-ounce regular beer
      • 5 ounces of wine
      • 1.5 ounces of distilled spirits or shot
    • If you drink 3 or more standard alcoholic drinks in the evening, skip your ADDYI dose at bedtime.
    • After you have taken your ADDYI at bedtime, do not drink alcohol until the following day.
  • take prescription medicines, over-the-counter medicines, or herbal supplements. Do not take or start taking any prescription medicines, over-the-counter medicines, or herbal supplements while taking ADDYI until you have talked with your doctor. Your doctor will tell you if it is safe to take other medicines or herbal supplements while you are taking ADDYI.
  • have liver problems. Do not take ADDYI if you have liver problems.

If you take ADDYI and you feel lightheaded or dizzy, lie down right away. Get emergency medical help or ask someone to get emergency medical help for you if the symptoms do not go away or if you feel like you could faint (lose consciousness). If you faint (lose consciousness), tell your doctor as soon as you can.

What is ADDYI?

ADDYI is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in women who have not gone through menopause, who have not had problems with low sexual desire in the past, and who have low sexual desire no matter the type of sexual activity, the situation, or the sexual partner. Women with HSDD have low sexual desire that is troubling to them. Their low sexual desire is not due to:

  • a medical or mental health problem
  • problems in the relationship
  • medicine or other drug use

ADDYI is not for use for the treatment of HSDD in women who have gone through menopause or in men.

ADDYI is not for use to improve sexual performance.

ADDYI is not for use in children.

What should I tell my doctor before taking ADDYI?

Before you take ADDYI, tell your doctor about all of your medical conditions, including if you:

  • drink alcohol, use drugs, or have a history of alcohol or drug abuse
  • have ever had depression or other mental health problems
  • have low blood pressure or a medical condition that can cause low blood pressure
  • are pregnant or plan to become pregnant. It is not known if ADDYI will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if ADDYI passes into your breast milk. You and your doctor should decide if you will take ADDYI or breastfeed. You should not do both.

Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. ADDYI can affect the way other medicines work, and other medicines can affect the way ADDYI works, and can cause serious side effects.

What are the possible side effects of ADDYI?

ADDYI can cause serious side effects, including:

  • Sleepiness is a common side effect of ADDYI and can be serious. Taking ADDYI can increase your risk of sleepiness if taken during waking hours, if you drink alcohol, or take certain medicines or herbal supplements.
  • Low blood pressure and fainting (loss of consciousness) can happen when you take ADDYI even if you do not drink alcohol or take other medicines or herbal supplements. Your risk of low blood pressure and fainting (loss of consciousness) is increased if ADDYI is taken during waking hours, if you drink alcohol within 2 hours of taking ADDYI, or if you take certain medicines or herbal supplements.

The most common side effects of ADDYI include:

  • Dizziness
  • Difficulty falling asleep or staying asleep
  • Nausea
  • Dry mouth
  • Tiredness

These are not all of the possible side effects of ADDYI. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

PRIVACY POLICY | LEGAL NOTICE

This site is intended for residents of the United States.

Addyi is a registered trademark of Sprout Pharmaceuticals, Inc. or its affiliates. All other trademarks are the property of their respective owners.

© 2019 Sprout Pharmaceuticals, Inc. US – – 1900058.07

References

1. Shifren JL, Monz BU, Russo PA, et al. Sexual problems and distress in United States women: prevalence and correlates. Obstet Gynecol. 2008;112(5):970-8.

2. Arnow BA, Millheiser L, Garrett A, et al. Women with hypoactive sexual desire disorder compared to normal females: A functional magnetic resonance imaging study. Neuroscience. 2009; 158:484-502.

3. Woodard TL, Nowak NT, Balon R, Diamond MP. Brain activation patterns in women with acquired hypoactive sexual desire disorder and women with normal sexual function: A cross-sectional pilot study. Fertil Steril. 2013; 100(4): 1068-1076.

4. Goldstein I, Kim N, Clayton AH, DeRogatis L, Giraldi A, Parish SJ, Pfaus J, Simon JA, Kingsberg SA, Meston C, Stahl SM, Wallen K, and Worsley R. Hypoactive Sexual Desire Disorder: International Society for the Study of Women’s Sexual Health (ISSWSH) Expert Consensus Panel Review. Mayo Clinic Proc. January 2017;92(1):114-128.

5. Clayton AH, Goldfischer ER, Goldstein I, DeRogatis L, Lewis‐D’Agostino DJ, and Pyke R. Validation of the Decreased Sexual Desire Screener (DSDS): A brief diagnostic instrument for generalized acquired female Hypoactive Sexual Desire Disorder (HSDD). J Sex Med 2009;6:730–738.